XDR™ Single-Use Bioreactors
XDR Single-Use Bioreactors from Xcellerex are fully-integrated, fully-characterized systems designed for GMP clinical and commercial production. XDR systems are available with working volumes of 50, 200, 500, 1,000 and 2,000 liters.
XDR has been proven to deliver stirred-tank performance that closely tracks and often exceeds the productivity of conventional stainless steel systems. Unlike conventional systems, XDR bioreactors can be delivered in 12 weeks and fully operational in hours. XDR also delivers robust return-on-investment (ROI).
And while the standard XDR configuration is highly optimized, the system's design can also be easily customized to tailor process variables for multi-drug production.
Xcellerex know-how is built into every XDR
Because Xcellerex scientists use XDR disposable bioreactors everyday, we are able to provide a level of predictive process understanding unavailable from other bioreactor makers. This know-how means your new optimized process will be up and running faster. And Xcellerex is the only bioreactor maker with a high-throughput process optimization platform and team under the same roof.
The XDR bioreactor is the heart of the FlexFactory™ platform and the engine of the Xcellerex inhouse biomanufacturing operation. The Xcellerex production team has used the XDR to test, optimize and run a wide range of cell lines including CHO, hybridoma, human, and insect cells. Xcellerex has even proven the XDR for challenging perfusion operations.
Why consider XDR Bioreactors?
Other disposables-based bioreactor systems require comparative analysis and testing to understand process set-up to achieve consistent high-quality reproducible performance. Characterization requires a many man-hours of integration, development, and process work.
With the XDR bioreactor, the Xcellerex team has designed a system that is characterized so that comparable results to traditional stainless systems can be achieved in the first process run.
XDR bioreactors offer proven GMP compliance and have developed a track record of exceeding performance targets set by our customers. This performance advantage derives from a unique mix offered only by Xcellerex:
Xcellerex delivers a fully-integrated, fully- characterized system that performs to customer expectations upon delivery. Start-up testing and programming are effectively non-existent.
Unlike stainless steel and other disposable bioreactors, XDR systems offer a level of flexibility that allows for rapid adjustment, and rapid optimization for nearly any process.
Xcellerex has fully-characterized the XDR system, and our scientists have run enough products through the bioreactor to gain a deep understanding of how to identify and manage process sensitivities.
All XDR bioreactor systems come with the Xcellerex Expedited Qualification of System (EQS) service, further speeding the integration process.
Xcellerex is uniquely able to:
Deliver a fully integrated and complete system, configured for your site and process.
Help set the initial conditions using a process model for the reactor.
Support you on-site to help install and commission the system.
Subsequently, Xcellerex maintains contact on a weekly basis to walk through questions and issues to assure a smooth integration. This access to the Xcellerex process team in the early stages of your experience helps simplify and accelerate successful start-up and operation.